LiSA, the Liquid Information Speaking Assistant, speaks with a real human voice when emails arrive, telling you who they are from:
LiSA understands replies so will also say: "You have a reply from your boss" LiSA can announce all incoming messages or only those where you have assigned relationships - it's your choice.
To use LiSA assign relationships with your contacts, such as brother, boss, lover and so on.
LiSA includes LiSA ringtones for your iPhone, which will be automatically installed into iTunes on installing LiSA. To use, go into your contacts on your iPhone and choose the relevant LiSA voicetones as the ringtones for the person.
LiSA OS X is FREE and available to DOWNLOAD